HIV-1 inhibitor-26

Names

[ CAS No. ]:
2415504-88-8

[ Name ]:
HIV-1 inhibitor-26

Biological Activity

[Description]:

HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[Target]

IC50: 1.4 μM (HIV-1 RT)[1]


[References]

[1]. Forezi LDSM, et al. Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors. Eur J Med Chem. 2020;194:112255.

Chemical & Physical Properties

[ Molecular Formula ]:
C43H33ClN2O9

[ Molecular Weight ]:
757.18

Related Compounds