BRM/BRG1 ATP Inhibitor-4

Names

[ CAS No. ]:
2422030-94-0

[ Name ]:
BRM/BRG1 ATP Inhibitor-4

Biological Activity

[Description]:

BRM/BRG1 ATP Inhibitor-4 is a BRG1/BRM inhibitor. BRM/BRG1 ATP Inhibitor-4 can be used for the research of cancers and BAF complex-related disorders[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[In Vivo]

BRM/BRG1 ATP Inhibitor-4 (QD; 5, 15, 50 mg/kg) leds to tumor growth inhibition in a dose-dependent manner[1]. Animal Model: Nude mice[1] Dosage: 5, 15, 50 mg/kg Administration: QD Result: Inhibited tumor growth and the size of tumors in mice engrafted with uveal melanoma cell lines.

[References]

[1]. Kevin J. Wilson, et al. Compounds and uses thereof. Patent. WO2021155320A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H32N6O3S

[ Molecular Weight ]:
496.62

Related Compounds