VEGFR-2-IN-27

Names

[ CAS No. ]:
2439096-14-5

[ Name ]:
VEGFR-2-IN-27

Biological Activity

[Description]:

VEGFR-2-IN-27 (compound 7a) is a highly potent VEGFR-2 inhibitor with an IC50 value of 14.8 nM. VEGFR-2-IN-27 can be used for researching anticancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR

[Target]

VEGFR-2:14.8 nM (IC50)


[References]

[1]. Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H21FN4O4

[ Molecular Weight ]:
460.46

Related Compounds