VIM-2-IN-1

Names

[ CAS No. ]:
2452118-54-4

[ Name ]:
VIM-2-IN-1

Biological Activity

[Description]:

VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 23 µM (VIM-2), 48 µM (GIM-1) and 231 µM (NDM-1)[1].


[References]

[1]. Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28(15):115598.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H13IN4O4S

[ Molecular Weight ]:
436.23

Related Compounds