Vitamin B5-13C3,15N hemicalcium hemihydrate

Vitamin B5-13C3,15N (hemicalcium hemihydrate) is the deuterium labeled Vitamin B5 (hemicalcium hemihydrate)[1].

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Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[35].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.