LDHA/PDKs-IN-1
Names
[ CAS No. ]:
2490699-40-4
[ Name ]:
LDHA/PDKs-IN-1
Biological Activity
[Description]:
LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C19H21FN2O4
[ Molecular Weight ]:
360.38