Thalidomide-O-C6-NHBoc

Names

[ CAS No. ]:
2509093-23-4

[ Name ]:
Thalidomide-O-C6-NHBoc

Biological Activity

[Description]:

Thalidomide-O-C6-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

Cereblon


[References]

[1]. Daniel A. HARKI, et al. Compounds that degrade kinases and uses thereof. WO2020247537A1.

[2]. Zhang NN, et al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020;182(5):1271-1283.e16.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H31N3O7

[ Molecular Weight ]:
473.52

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds