BTK-IN-23
Names
[ CAS No. ]:
2573048-11-8
[ Name ]:
BTK-IN-23
Biological Activity
[Description]:
BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1].
[Related Catalog]:
[In Vitro]
BTK-IN-23 (化合物 3) 抑制 Jeko-1 细胞中的 BTK 自磷酸化,IC50 为 314 nM[1]。 Western Blot Analysis[1] Cell Line: Jeko-1 cell Concentration: 0.01, 0.1, 1, 10 μM Incubation Time: 2 h Result: Inhibited BTK autophosphorylation.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C27H28N6O2
[ Molecular Weight ]:
468.55