p53 Activator 5

Names

[ CAS No. ]:
2636840-37-2

[ Name ]:
p53 Activator 5

Biological Activity

[Description]:

p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> MDM-2/p53

[References]

[1]. VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H32F6N4O

[ Molecular Weight ]:
566.58

Related Compounds