SOS1-IN-13

Names

[ CAS No. ]:
2654741-45-2

[ Name ]:
SOS1-IN-13

Biological Activity

[Description]:

SOS1-IN-13 is a potent son of sevenless homolog 1 (SOS1) inhibitor with IC50s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 can be used for researching anticancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

IC50: 6.5 nM (SOS1), 327 nM (pERK)[1]


[References]

[1]. Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 4-1)

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22F3N3O2

[ Molecular Weight ]:
405.41

Related Compounds