RORγt agonist 2

Names

[ CAS No. ]:
2663787-92-4

[ Name ]:
RORγt agonist 2

Biological Activity

[Description]:

RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17)[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR
Research Areas >> Inflammation/Immunology

[References]

[1]. Liu Bin, et al. Amides with bicyclic structures and their applications in pharmaceuticals. Patent WO2021136339A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H30F3N3O4S

[ Molecular Weight ]:
585.64

Related Compounds