ATX inhibitor 21

Names

[ CAS No. ]:
2691936-89-5

[ Name ]:
ATX inhibitor 21

Biological Activity

[Description]:

ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

Autotaxin:3490 ± 170 nM (IC50)

[References]

[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₅F₂N₅O₂S

[ Molecular Weight ]:
509.57

Related Compounds