ATX inhibitor 17
Names
[ CAS No. ]:
2750152-64-6
[ Name ]:
ATX inhibitor 17
Biological Activity
[Description]:
ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].
[Related Catalog]:
[Target]
IC50: 0.019 µM (ATX)[1]
[In Vitro]
ATX inhibitor 17 (compound 25a) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1]. Cell Cytotoxicity Assay[1] Cell Line: MCF7, MDA-MB-231, A549, H2228 cells Concentration: 0-15 µM Incubation Time: 72 h Result: Showed excellent antiproliferative effects with IC50s of 1.01, 0.79, 13.40, >15 µM for MCF7, MDA-MB-231, A549, H2228 cells, respectively.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C29H29F5N8S
[ Molecular Weight ]:
616.65