SARS-CoV-2 Mpro-IN-1

Names

[ CAS No. ]:
2758359-91-8

[ Name ]:
SARS-CoV-2 Mpro-IN-1

Biological Activity

[Description]:

SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), with an IC50 of 116 nM[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Chen W, et, al. Discovery of highly potent SARS-CoV-2 M pro inhibitors based on benzoisothiazolone scaffold. Bioorg Med Chem Lett. 2022 Feb 15;58:128526.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H11FN2O2S

[ Molecular Weight ]:
302.32


Related Compounds