BTK-IN-10

Names

[ CAS No. ]:
2758596-07-3

[ Name ]:
BTK-IN-10

Biological Activity

[Description]:

BTK-IN-10 is a potent BTK inhibitor with IC50s of <5 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022012509A1; example 111)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Chunchao Yue, et al. Compound as brain-permeable btk or her2 inhibitor, preparation method therefor, and use thereof. WO2022012509A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H24F2N4O2

[ Molecular Weight ]:
450.48

Related Compounds