KRAS G12D inhibitor 17

Names

[ CAS No. ]:
2821793-99-9

[ Name ]:
KRAS G12D inhibitor 17

Biological Activity

[Description]:

KRAS G12D inhibitor 17 (example 8) is a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, inducing degradation of G12D-mutation KRAS protein[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS(G12D)


[References]

[1]. Yoshinari, et al. Preparation of quinazoline-linked (4R)-4-hydroxy-L-prolinamide compounds for inducing degradation of G12D-mutation KRAS protein: World Intellectual Property Organization, WO2022173032[P]. 2022-08-18.

Chemical & Physical Properties

[ Molecular Formula ]:
C60H65FN12O7S

[ Molecular Weight ]:
1117.30

Related Compounds