Tetramethyl-ammonium Bromide-d12

Names

[ CAS No. ]:
284474-82-4

[ Name ]:
Tetramethyl-ammonium Bromide-d12

[Synonym ]:
Tetramethyl-d12-ammonium bromide

Biological Activity

[Description]:

Tetramethyl-ammonium Bromide-d12 is the deuterium labeled TMAB[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C₄BrD₁₂N

[ Molecular Weight ]:
166.12300

[ Exact Mass ]:
165.09100

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
25-36/37/38

[ Safety Phrases ]:
26-45

[ RIDADR ]:
UN 2811 6.1/PG 2