WAY-622024

Names

[ Name ]:
WAY-622024

[Synonym ]:
4-cyclopropylamino-3-nitro-benzoic acid

Biological Activity

[Description]:

GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GPR109A

Research Areas >> Metabolic Disease

[References]

[1]. Skinner PJ, et al. 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6619-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₀N₂O₄

[ Molecular Weight ]:
222.20

[ Exact Mass ]:
222.06400

[ PSA ]:
95.15000

[ LogP ]:
2.46350

[ Storage condition ]:
-20°C