(2H5)Phenylmethyl (2E)-3-phenylacrylate

Names

[ CAS No. ]:
347840-02-2

[ Name ]:
(2H5)Phenylmethyl (2E)-3-phenylacrylate

[Synonym ]:
(H)Phenylmethyl (2E)-3-phenylacrylate
2-Propenoic acid, 3-phenyl-, phenyl-d-methyl ester, (2E)-

Biological Activity

[Description]:

Benzyl cinnamate-d5 is the deuterium labeled Benzyl cinnamate[1]. Benzyl cinnamate, occurs in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, is used in heavy oriental perfumes and as a fixative[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Bhatia SP, et al. Fragrance material review on benzyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S40-8. Epub 2007 Sep 14.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
371.2±11.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H9D5O2

[ Molecular Weight ]:
243.312

[ Flash Point ]:
225.7±10.4 °C

[ Exact Mass ]:
243.130768

[ PSA ]:
26.30000

[ LogP ]:
3.65

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.608

Related Compounds