JTC-017
Names
[ CAS No. ]:
357330-77-9
[ Name ]:
JTC-017
[Synonym ]:
Benzamide,3,5-dichloro-N-(5-((diethylamino)sulfonyl)-3-(dimethylamino)-2-methoxyphenyl)-4-hydroxy
JTC-017
UNII-7F4TZ7XGMO
Biological Activity
[Description]:
JTC-017, a specific corticotropin-releasing hormone receptor 1 antagonist, attenuates hippocampal noradrenaline release, visceral perception, adrenocorticotropic hormone release, and anxiety after acute colorectal distention in rats. JTC-017 blocks stress-induced changes in colonic motility after chronic colorectal distention in rats[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H25Cl2N3O5S
[ Molecular Weight ]:
490.40100
[ Exact Mass ]:
489.08900
[ PSA ]:
111.05000
[ LogP ]:
5.52120