Aposcopolamine

Names

[ CAS No. ]:
535-26-2

[ Name ]:
Aposcopolamine

[Synonym ]:
Atropasaeure-(6exo,7exo-epoxy-tropan-3endo-ylester),O-Atropoyl-scopin
Atropasaeure-(6exo,7exo-epoxy-tropan-3endo-ylester)
aposcopolamine
2-phenyl-acrylic acid 9-methyl-(1rN,2tH,4tH,5cN)-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7t-yl ester
Aposcopolamin
atropic acid-(6exo,7exo-epoxy-tropane-3endo-yl ester)
OSCINE ATROPATE
6,7-Epoxy-3-atropolyoxytropane
a-Methylenebenzeneacetic Acid (1a,2,4,5a,7)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester

Biological Activity

[Description]:

Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Yi P, et al. Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease. Pharm Biol. 2020 Dec;58(1):932-943.

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
415.5ºC at 760mmHg

[ Melting Point ]:
95-98ºC

[ Molecular Formula ]:
C₁₇H₁₉NO₃

[ Molecular Weight ]:
285.33800

[ Flash Point ]:
205.1ºC

[ Exact Mass ]:
285.13600

[ PSA ]:
42.07000

[ LogP ]:
1.79330

[ Index of Refraction ]:
1.604

[ Storage condition ]:
-20°C Freezer

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%