Diethylstilbestrol-d3

Names

[ CAS No. ]:
58322-36-4

[ Name ]:
Diethylstilbestrol-d3

Biological Activity

[Description]:

Diethylstilbestrol-d3 is deuterium labeled Diethylstilbestrol.

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR
Research Areas >> Cancer
Research Areas >> Endocrinology

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Troisi, R., et al., Medical conditions among adult offspring prenatally exposed to diethylstilbestrol. Epidemiology, 2013. 24(3): p. 430-8.

[3]. Kebir, O. and M.O. Krebs, Diethylstilbestrol and risk of psychiatric disorders: a critical review and new insights. World J Biol Psychiatry, 2012. 13(2): p. 84-95.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H17D3O2

[ Molecular Weight ]:
271.37

Related Compounds