AHR-5333

Names

[ CAS No. ]:
60284-71-1

[ Name ]:
AHR-5333

[Synonym ]:
Ahr 5333

Biological Activity

[Description]:

AHR-5333 is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase

[Target]

60284-71-1


[References]

[1]. J M Yanni, et al. Effects of AHR-5333, a new potential antiallergy compound, in in vivo models of immediate hypersensitivity. Int Arch Allergy Appl Immunol. 1988;85(4):428-33.  

[2]. G. Graff, et al. 1-[4-[3-[4-[Bis (4-fluorophenyl) hydroxymethyl]-1-piperidinyl] propoxy]-3]-methoxyphenyl] ethanone (AHR-5333): A selective human blood neutrophil 5-lipoxygenase inhibitor. Prostaglandins. Volume 38, Issue 4, October 1989, Pages 473-496

Chemical & Physical Properties

[ Molecular Formula ]:
C30H33F2NO4

[ Molecular Weight ]:
509.58400

[ Exact Mass ]:
509.23800

[ PSA ]:
59.00000

[ LogP ]:
5.53090

Related Compounds