Wy 41747

Names

[ CAS No. ]:
68463-41-2

[ Name ]:
Wy 41747

[Synonym ]:
(4R,7S,10S,11E,13S,16S,19S,22R,23E,25S,26E,28S,31S,34S,35E,37R)-37-Amino-19-(4-aminobutyl)-13,25,28-tribenzyl-6,9,12,15,18,21,24,27,30,33,36-undecahydroxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-31,34-bis(1H-imidazol-5-ylmethyl)-22-(1H-indol-3-ylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,14,17,20,23,26,29,32,35-undecaene-4-carboxylic acid
1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,14,17,20,23,26,29,32,35-undecaene-4-carboxylic acid, 37-amino-19-(4-aminobutyl)-6,9,12,15,18,21,24,27,30,33,36-undecahydroxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-31,34-bis(1H-imidazol-5-ylmethyl)-22-(1H-indol-3-ylmethyl)-13,25,28-tris(phenylmethyl)-, (4R,7S,10S,11E,13S,16S,19S,22R,23E,25S,26E,28S,31S,34S,35E,37R)-
Des-ala1

Biological Activity

[Description]:

Wy 41747 is a long-acting Somatostatin analogue. Wy 41747 can be used for the research of diabetes mellitus[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[In Vitro]

Wy 41747 可以改善 I 型糖尿病患者的糖尿病控制[1]。

[References]

[1]. Dimitriadis G, et, al. Effects of a long-acting somatostatin analogue on postprandial hyperglycemia in insulin-dependent diabetes mellitus. Metabolism. 1983 Oct;32(10):987-92.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1749.2±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C73H92N18O16S2

[ Molecular Weight ]:
1541.753

[ Flash Point ]:
1011.7±37.1 °C

[ Exact Mass ]:
1540.638062

[ LogP ]:
-6.23

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.710

Related Compounds