Hinnuliquinone

Names

[ CAS No. ]:
78860-37-4

[ Name ]:
Hinnuliquinone

[Synonym ]:
hinnuliquinone

Biological Activity

[Description]:

Hinnuliquinone is a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease. Hinnuliquinone is a bis-indolyl-2,5-dihydroxybenzoquinone pigment, that can be isolated from Nodulisphorium hinnuleum[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease

[Target]

HIV-1


[References]

[1]. O&#X, et al. Hinnuliquinone, a bis-indolyl-2,5-dihydroxybenzoquinone pigment from nodulisphorium hinnuleum[J]. Tetrahedron Letters, 1982, 23( 17):1855-1856.

[2]. Singh SB, et al. Hinnuliquinone, a C2-symmetric dimeric non-peptide fungal metabolite inhibitor of HIV-1 protease. Biochem Biophys Res Commun. 2004 Nov 5;324(1):108-13.  

Chemical & Physical Properties

[ Molecular Formula ]:
C32H30N2O4

[ Molecular Weight ]:
506.59200

[ Exact Mass ]:
506.22100

[ PSA ]:
106.18000

[ LogP ]:
6.96660

Precursor & DownStream

Precursor

DownStream