Androst-4-en-3-one-16,16,17-d3, 17-[(1-oxodecyl)oxy]-, (17β)

Names

[ Name ]:
Androst-4-en-3-one-16,16,17-d3, 17-[(1-oxodecyl)oxy]-, (17β)

[Synonym ]:
Testosterone-16,16,17-d3Decanoate
TESTOSTERONE-D3 DECANOATE

Biological Activity

[Description]:

Testosterone decanoate-d3 is the deuterium labeled Testosterone decanoate. Testosterone decanoate is a naturally occurring androgen testosterone ester. Testosterone decanoate shows long-acting male antifertility effects.

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Others >> Androgen Receptor

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

[2]. Rijk JCW, et, al. Bioassay based screening of steroid derivatives in animal feed and supplements. Anal Chim Acta. 2011 Aug 26;700(1-2):183-8.

[3]. Nielen MWF, et, al. Feasibility of desorption electrospray ionization mass spectrometry for rapid screening of anabolic steroid esters in hair. Anal Chim Acta. 2011 Aug 26;700(1-2):63-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₆O₃

[ Molecular Weight ]:
442.67400

[ Exact Mass ]:
442.34500

[ PSA ]:
43.37000

[ LogP ]:
7.57080