SARS-CoV-2 nsp13-IN-6

Names

[ CAS No. ]:
951588-85-5

[ Name ]:
SARS-CoV-2 nsp13-IN-6

Biological Activity

[Description]:

SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

IC50: 27 μM (ssDNA+ ATPase), 33 μM (ssDNA- ATPase)[1]


[References]

[1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19N5O3S

[ Molecular Weight ]:
421.47

Related Compounds