N-Tetradecanoyl-DL-homoserine lactone

Names

[ Name ]:
N-Tetradecanoyl-DL-homoserine lactone

[Synonym ]:
3-tetradecanoylamino-dihydro-furan-2-one
N-Myristoyl-DL-homoserine lactone
Homoserine lactone,N-tetradecanoyl
ACF65EBA-3613-47D0-85B1-F1A6A4A8889C
N-tetradecanoylhomoserine lactone
MFCD01862913
N-tetradecanoyl-HSL
N-tetradecanoyl-DL-homoserine lactone

Biological Activity

[Description]:

N-Tetradecanoyl-DL-homoserine lactone is a serine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₃NO₃

[ Molecular Weight ]:
311.46000

[ Exact Mass ]:
311.24600

[ PSA ]:
58.89000

[ LogP ]:
4.95950

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.

Microbiology 143 , 3703, (1997)

Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, s...

Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila.

Infect. Immun. 67 , 5192-5199, (1999)

In Aeromonas hydrophila, the ahyI gene encodes a protein responsible for the synthesis of the quorum sensing signal N-butanoyl-L-homoserine lactone (C4-HSL). Inactivation of the ahyI gene on the A. hy...

Detection of acyl-homoserine lactones by Escherichia and Salmonella.

Curr. Opin. Microbiol. 14 , 188-193, (2011)

Escherichia and Salmonella do not synthesize quorum-sensing signaling molecules of the N-acyl-l-homoserine lactone (AHL) type but they can detect AHLs produced by other species of bacteria. AHLs are p...