2,6-Dimethoxy-1,4-benzoquinone

Names

[ CAS No. ]:
530-55-2

[ Name ]:
2,6-Dimethoxy-1,4-benzoquinone

[Synonym ]:
2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-
2,6-Dimethoxyquinone
2,6-dimethoxy-p-quinone
2,6-Dimethoxy-1,4-benzoquine
2,6-Dimethoxybenzo-1,4-quinone
2,6-Dimethoxy-2,5-cyclohexadiene-1,4-dione
Dimethoxybenzoquinone,2,6
MFCD00016368
2,6-Dimethoxycyclohexa-2,5-diene-1,4-dione
2,6-dimethoxy-p-benzoquinon
dmbq
2,6-Dimethoxy-1,4-benzoquinone
2,6-dimethoxy-p-benzoquinone
2,6-Dimethoxybenzoquinone
EINECS 208-484-7
2,5-DIHYDROXYBENZOQUINONE

Biological Activity

[Description]:

2,6-Dimethoxy-1,4-benzoquinone, a natural phytochemical, is a known haustorial inducing factor. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimalaria effects[1].子

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Tomonori Kamiya , et al. 2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae. Food Chem Toxicol. 2018 Dec;122:172-180.

[2]. Jennifer Mach. A shot in the dark: how parasitic plants find host roots Plant Cell. 2010 Apr;22(4):995.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
311.1±42.0 °C at 760 mmHg

[ Melting Point ]:
253-257 °C (dec.)(lit.)

[ Molecular Formula ]:
C₈H₈O₄

[ Molecular Weight ]:
168.147

[ Flash Point ]:
139.2±27.9 °C

[ Exact Mass ]:
168.042252

[ PSA ]:
52.60000

[ LogP ]:
0.28

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Stability ]:
Stable. Combustible. Incompatible with oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK4750000

CHEMICAL NAME :: p-Benzoquinone, 2,6-dimethoxy-

CAS REGISTRY NUMBER :: 530-55-2

LAST UPDATED :: 198909

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C8-H8-O4

MOLECULAR WEIGHT :: 168.16

WISWESSER LINE NOTATION :: L6V DVJ BO1 FO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: DNA damage

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 10 umol/L

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 244,1011,1988

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DK4750000

[ HS Code ]:
2914690090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914690090

[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Oxidative depolymerization of lignin in ionic liquids.

ChemSusChem 3(6) , 719-23, (2010)

Beech lignin was oxidatively cleaved in ionic liquids to give phenols, unsaturated propylaromatics, and aromatic aldehydes. A multiparallel batch reactor system was used to screen different ionic liqu...

Quinonoid constituents as contact sensitisers in Australian blackwood (Acacia melanoxylon RBR).

Br. J. Ind. Med. 38(2) , 105-9, (1981)

Australian blackwood (Acacia melanoxylon RBR) is a valuable commercial timber that since 1925 has been incriminated as being injurious to health. In addition to toxic effects numerous cases of allergi...

Orchid allergy.

Arch. Dermatol. 120(9) , 1206-8, (1984)

A female office worker acquired contact allergy by handling Cymbidium cultivars for several years. The sensitizing properties of this ornamental orchid were demonstrated by experimental sensitization ...