nelumol a

Names

[ Name ]:
nelumol a

[Synonym ]:
O-Geranylsinapyl alcohol
2-Propen-1-ol, 3-[4-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-3,5-dimethoxyphenyl]-, (2E)-
(2E)-3-(4-{[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy}-3,5-dimethoxyphenyl)-2-propen-1-ol
(E,E)-3-(4-((3,7-Dimethyl-2,6-octadienyl)oxy)-3,5-dimethoxyphenyl)-2-propen-1-ol
Nelumol A
2-Propen-1-ol, 3-(4-((3,7-dimethyl-2,6-octadienyl)oxy)-3,5-dimethoxyphenyl)-, (E,E)-
4-O-geranyl-sinapyl alcohol
geranyloxy sinapyl alcohol

Biological Activity

[Description]:

Nelumol A is a farnesoid X receptor (FXR) agonist[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Research Areas >> Inflammation/Immunology

[References]

[1]. Francesco Epifano, et al. Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. Bioorg Med Chem Lett. 2012 May 1;22(9):3130-5.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
500.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₃₀O₄

[ Molecular Weight ]:
346.46

[ Flash Point ]:
256.5±30.1 °C

[ Exact Mass ]:
346.214417

[ PSA ]:
47.92000

[ LogP ]:
5.20

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.540

Safety Information

[ Hazard Codes ]:
Xi

nelumol a

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds