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Vibralactone D

Names

[ CAS No. ]:
1251748-32-9

[ Name ]:
Vibralactone D

[Synonym ]:
(1R,5S,7S)-7-Hydroxy-1-(3-methyl-2-buten-1-yl)-3-oxabicyclo[3.2.1]octan-2-one
3-Oxabicyclo[3.2.1]octan-2-one, 7-hydroxy-1-(3-methyl-2-buten-1-yl)-, (1R,5S,7S)-

Biological Activity

[Description]:

Vibralactone D (Compound 1) is a metabolite isolated and cultured from natural basidiomycetes Boreostereum vibrans. Vibralactone D shows weak inhibitory activity against isoenzymes of 11b-hydroxysteroid dehydrogenase (HSD) (IC50 85.7 μM).

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Jiang MY, et al. Vibralactones D-F from cultures of the basidiomycete Boreostereum vibrans. Chem Pharm Bull (Tokyo). 2010 Jan;58(1):113-6.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
362.5±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H18O3

[ Molecular Weight ]:
210.27

[ Flash Point ]:
155.3±15.9 °C

[ Exact Mass ]:
210.125595

[ LogP ]:
1.05

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.533

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds