Tirucallol

Names

[ CAS No. ]:
514-46-5

[ Name ]:
Tirucallol

[Synonym ]:
Lanosta-8,24-dien-3-ol
Tirucalladienol

Biological Activity

[Description]:

Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Fernandez-Arche A, et, al. Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex. Phytomedicine. 2010 Feb;17(2):146-8.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
498.9±44.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₅₀O

[ Molecular Weight ]:
426.717

[ Flash Point ]:
221.1±20.7 °C

[ Exact Mass ]:
426.386169

[ PSA ]:
20.23000

[ LogP ]:
11.00

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.530

Safety Information

[ Hazard Codes ]:
Xi