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Panaxadiol

Names

[ CAS No. ]:
19666-76-3

[ Name ]:
Panaxadiol

[Synonym ]:
PALMITIC ACID METHYLESTER(RG) (SEE METHYL PALMITATE)
(3β,12β,20R)-20,25-Epoxydammarane-3,12-diol
Panaxaidol
DAMMARANE-3BETA,12BETA-DIOL
Dammarane-3,12-diol, 20,25-epoxy-, (3β,12β,20R)-
Panaxadio

Biological Activity

[Description]:

Panaxadiol is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer
Natural Products >> Terpenoids and Glycosides

[References]

[1]. Xiaojun C, et al. An UFLC-MS/MS method for quantification of panaxadiol in rat plasma and its application to a pharmacokinetic study. Planta Med. 2013 Sep;79(14):1324-8.

[2]. Tae-Hoon Kim, et al. The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart. Food and Chemical ToxicologyVolume 48, Issue 6, June 2010, Pages 1516–1520


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
531.3±45.0 °C at 760 mmHg

[ Melting Point ]:
247 °C

[ Molecular Formula ]:
C30H52O3

[ Molecular Weight ]:
460.732

[ Flash Point ]:
275.1±28.7 °C

[ Exact Mass ]:
460.391632

[ PSA ]:
49.69000

[ LogP ]:
7.64

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.515

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

Related Compounds