Naringin
Names
[ CAS No. ]:
10236-47-2
[ Name ]:
Naringin
[Synonym ]:
2,6-Dimethylpyrimidin-4(1H)-one
2,6-Dimethylpyrimidin-4-ol
Naringenin 7-neohesperidoside
MFCD00148888
2,6-Dimethyl-4(1H)-pyrimidinone
T6N CNJ B1 DQ F1
T6VM DNJ C1 E1
EINECS 233-566-4
2,6-Dimethyl-4(3H)-pyrimidinone
Naringenin 7-Rhamnoglucoside Hydrate
Naringenoside
Nobiletin
Naringin Hydrate
2,6-Dimethylpyrimidin-4(3H)-one
4(3H)-Pyrimidinone, 2,6-dimethyl-
4-pyrimidinol, 2,6-dimethyl-
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
928.1±65.0 °C at 760 mmHg
[ Melting Point ]:
166 °C
[ Molecular Formula ]:
C27H32O14
[ Molecular Weight ]:
580.53
[ Flash Point ]:
308.5±27.8 °C
[ PSA ]:
225.06000
[ LogP ]:
-0.18
[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.564
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QN6340000
- CHEMICAL NAME :
- Naringin
- CAS REGISTRY NUMBER :
- 10236-47-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C27-H32-O14
- MOLECULAR WEIGHT :
- 580.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 19,207,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 19,207,1980
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QN6340000
Precursor & DownStream
Precursor
DownStream
Articles
PLoS ONE 10 , e0132429, (2015)
Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have i...
Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.PLoS ONE 10 , e0132791, (2015)
Recently, extracts of Dalbergia trichocarpa bark have been shown to disrupt P. aeruginosa PAO1 quorum sensing (QS) mechanisms, which are key regulators of virulence factor expression and implicated in...
The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin.Food Chem. Toxicol. 81 , 160-70, (2015)
Phenolic compounds not only contribute to the sensory qualities of fruits and vegetables but also exhibit several health protective properties. Limonene and naringin are the most popular phenolics fou...