Thiohydantoin Price from Supplier Brand ShangHai DC Chemicals Co.,Ltd on Chemsrc.com

Published date: 2022-11-29 15:44:27

CAS number: 503-87-7

Price:
￥Inquiry/1g

Purity: 98.9%

Stocking period: 1 Day

Stock: In Stock

Detail Product Information:
Thiohydantoin, also known as 2-Thiohydantoin and NSC 11772, is a potent inhibitors of mutant IDH1. Thiohydantoin can decrease the cellular concentration of D2HG, reduce the levels of histone methylation, and suppress the proliferation of stem-like cancer cells in BT142 glioma with IDH1 R132H mutation. Somatic mutations of isocitrate dehydrogenase 1 (IDH1) at R132 are frequently found in certain cancers such as glioma. With losing the activity of wild-type IDH1, the R132H and R132C mutant proteins can reduce α-ketoglutaric acid (α-KG) to d-2-hydroxyglutaric acid (D2HG).

Name: ShangHai DC Chemicals Co.,Ltd Recommended

Chemsrc Level: Verified

Product #: 14107

Tel: 58447131

Address: Pudong new area Jin Yu road 100#

Area: China(Mainland)

Contact: Tony Lai

Contact Phone #: 13564518121

Email: order@dcchemicals.com

Website: http://www.biomedgen.cn

Foreign Trade % of Salers: 20%

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