Prometryn
Names
[ CAS No. ]:
7287-19-6
[ Name ]:
Prometryn
[Synonym ]:
1,3,5-Triazine-2,4-diamine, N,N'-bis(1-methylethyl)-6-(methylthio)-
N,N'-Diisopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine
Prometryne
Uvon
6-methylsulfanyl-2-N,4-N-di(propan-2-yl)-1,3,5-triazine-2,4-diamine
N2,N4-diisopropyl-6-methylthio-1,3,5-triazine-2,4-diamine
6-(methylsulfanyl)-N2,N4-di(propan-2-yl)-1,3,5-triazine-2,4-diamine
Primatol Q
N,N'-bis(1-methylethyl)-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine
2-methylmercapto-4,6-diisopropylamino-1,3,5-triazine
EINECS 230-711-3
1,3,5-Triazine-2,4-diamine, N,N-bis(1-methylethyl)-6-(methylthio)-
N,N’-bis(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine
Merin
2-Propanamine, N,N'-[6-(methylthio)-1,3,5-triazine-2,4(1H,3H)-diylidene]bis-
Prometrex
Gesagard
(2Z,4E)-N,N'-Diisopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4(1H,3H)-diimine
MFCD00055396
Prometryn
Mercazin
Caparol
Selectin
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
322.8±25.0 °C at 760 mmHg
[ Melting Point ]:
118-120°C
[ Molecular Formula ]:
C10H19N5S
[ Molecular Weight ]:
241.356
[ Flash Point ]:
149.0±23.2 °C
[ Exact Mass ]:
241.136108
[ PSA ]:
88.03000
[ LogP ]:
1.91
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.602
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XY4390000
- CHEMICAL NAME :
- s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)-
- CAS REGISTRY NUMBER :
- 7287-19-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C10-H19-N5-S
- MOLECULAR WEIGHT :
- 241.40
- WISWESSER LINE NOTATION :
- T6N CN ENJ BS1 DMY1&1 FMY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2430 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >3100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2138 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - urine volume increased
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >3100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14223 mg/kg/7W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in adrenal weight Blood - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2400 mg/kg
- SEX/DURATION :
- female 18-20 day(s) after conception lactating female 2-4 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - physical Reproductive - Effects on Newborn - delayed effects
MUTATION DATA
- TYPE OF TEST :
- Gene conversion and mitotic recombination
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 500 ug/L
- REFERENCE :
- CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 21(2),59,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3180 No. of Facilities: 167 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1169 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3180 No. of Facilities: 13 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 567 (estimated) No. of Female Employees: 13 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H332-H400
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
F,Xn,N
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
S16-S26-S36-S61-S60
[ RIDADR ]:
UN 1648 3/PG 2
[ RTECS ]:
XY4390000
[ HS Code ]:
3808931100
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 3808931100
Articles
Environ. Toxicol. Chem. 30(3) , 622-31, (2011)
Rates of pesticide degradation in aquatic ecosystems often differ between those observed within laboratory studies and field trials. Under field conditions, a number of additional processes may well h...
Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L.).Neuro Endocrinol. Lett. 33 Suppl 3 , 130-5, (2012)
The aim of the study was to investigate effects of the triazine herbicide prometryne on early life stages of common carp Cyprinus carpio as indicated by oxidative stress and antioxidant indices.Toxici...
Quantitative analysis of triazine herbicides in environmental samples by using high performance liquid chromatography and diode array detection combined with second-order calibration based on an alternating penalty trilinear decomposition algorithm.Anal. Chim. Acta 678(1) , 26-33, (2010)
A novel application of second-order calibration method based on an alternating penalty trilinear decomposition (APTLD) algorithm is presented to treat the data from high performance liquid chromatogra...