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EUK 118

Names

[ CAS No. ]:
186299-34-3

[ Name ]:
EUK 118

Biological Activity

[Description]:

EUK-118 is an analog of EUK 8 and EUK 134 with reduced activity. EUK-118 exhibits superoxide dismutase (SOD) mimetic activity[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Doctrow SR, et, al. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies. J Med Chem. 2002 Sep 26;45(20):4549-58.

[2]. Vera M, et, al. Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease. Cell Physiol Biochem. 2018;51(3):1287-1300.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₅Mn₃N₂O₈

[ Molecular Weight ]:
610.25700

[ Exact Mass ]:
609.97500

[ PSA ]:
129.19000

[ LogP ]:
0.57260

Related Compounds