Quetiapine Fumarate
Names
[ CAS No. ]:
111974-72-2
[ Name ]:
Quetiapine Fumarate
[Synonym ]:
MFCD03423782
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
Quetiapine Hemifumarate
2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol 2-butenedioate (2:1)
Quetiapine fumarate
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, 2-butenedioate (2:1) (salt)
Quetiapine hemifumarate salt
Quetiapine (fumarate)
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Boiling Point ]:
556.5ºC at 760 mmHg
[ Melting Point ]:
174-176°C
[ Molecular Formula ]:
C23H27N3O4S
[ Molecular Weight ]:
441.54
[ Flash Point ]:
290.4ºC
[ PSA ]:
221.80000
[ LogP ]:
4.04660
[ Vapour Pressure ]:
3.22E-13mmHg at 25°C
[ Storage condition ]:
-20°C Freezer
MSDS
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H400
[ Precautionary Statements ]:
P273
[ Hazard Codes ]:
T,F
[ Risk Phrases ]:
R45:May cause cancer. R10:Flammable.
[ Safety Phrases ]:
S53-S45
[ RIDADR ]:
UN 3295 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
PC1075000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Neural Transm. Gen. Sect. 121(11) , 1337-47, (2014)
The dopaminergic stabilizers pridopidine [4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine] and ordopidine [1-ethyl-4-(2-fluoro-3-(methylsulfonyl)phenyl)piperidine] inhibit psychostimulant-induced hype...
An understanding of modified release matrix tablets behavior during drug dissolution as the key for prediction of pharmaceutical product performance - case study of multimodal characterization of quetiapine fumarate tablets.Int. J. Pharm. 484(1-2) , 235-45, (2015)
Motivation for the study was the lack of dedicated and effective research and development (R&D) in vitro methods for oral, generic, modified release formulations. The purpose of the research was to as...
Quetiapine for the treatment of cocaine use disorder.Drug Alcohol Depend. 149 , 18-24, (2015)
Cocaine addiction continues to be a significant healthcare issue, yet there are no FDA approved medications for the treatment of cocaine use disorder within the United States.This 12-week, prospective...