3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID
Names
[ CAS No. ]:
227619-64-9
[ Name ]:
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID
[Synonym ]:
hip-a
Biological Activity
[Description]:
(±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C6H8N2O4
[ Molecular Weight ]:
172.14
[ Exact Mass ]:
172.04800
[ PSA ]:
91.15000