Psychosine
Names
[ CAS No. ]:
2238-90-6
[ Name ]:
Psychosine
[Synonym ]:
Galactosylsphingosine
D-galactosyl-ß1-1'-D-erythro-sphingosine
1-B-D-GALACTOSYLSPHINOGOSINE
Psychosine from bovine brain
PSYCHOSIN
PSYCHOSINE
D-GALACTOSYL-B1-1' SPHINGOSN
LYSO-CERAMIDEGALACTOSIDE
MFCD00057505
O-Galactosylsphingosine
LYSO-CEREBROSIDE
Biological Activity
[Description]:
[Related Catalog]:
[Target]
PKC
[In Vitro]
[References]
Chemical & Physical Properties
[ Density]:
1.14 g/cm3
[ Boiling Point ]:
664.3ºC
[ Molecular Formula ]:
C24H47NO7
[ Molecular Weight ]:
461.63200
[ Flash Point ]:
355.6ºC
[ Exact Mass ]:
461.33500
[ PSA ]:
145.63000
[ LogP ]:
2.44870
[ Vapour Pressure ]:
1.77E-20mmHg at 25°C
[ Index of Refraction ]:
1.535
[ Storage condition ]:
−20°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
36
[ RIDADR ]:
NONH for all modes of transport
Precursor & DownStream
Precursor
DownStream
Articles
Clin. Chim. Acta 411(23-24) , 1906-14, (2010)
Fabry disease is characterized by accumulation of glycosphingolipids, such as globotriaosylceramide (Gb(3)), in many tissues and body fluids. A novel plasma biomarker, globotriaosylsphingosine (lyso-G...
Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions.J. Neuropathol. Exp. Neurol. 73(10) , 964-74, (2014)
Globoid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galacto...
Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy.J. Neurosci. 31(27) , 9945-57, (2011)
Globoid-cell leukodystrophy (GLD) is an inherited demyelinating disease caused by the deficiency of the lysosomal enzyme galactosylceramidase (GALC). A previous study in the murine model of GLD (twitc...