LY2886721

Names

[ CAS No. ]:
1262036-50-9

[ Name ]:
LY2886721

[Synonym ]:
LY-2886721
cc-426
S2156_Selleck
UNII:2CQ62IWB67
LY2886721
UNII-2CQ62IWB67
LY 2886721

Biological Activity

[Description]:

LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.IC50 value:Target: BACELY2886721 is a novel potent agent that is used to treat Alzheimer’s Disease in preclinical experiments. LY2886721 is under clinical study. A Safety Study of LY2886721 Multiple Doses is performing in Healthy Subjects.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

[References]

[1]. A Safety Study of LY2886721 Multiple Doses in Healthy Subjects

[Related Small Molecules]

MK-8931 | AZD3293(Lanabecestat) | LY2811376 | Epiberberine chloride | AZD3839 | LX-2343 | PF-06751979 | Sophoflavescenol | BACE-IN-1 | BACE1-IN-1 | β-Secretase Inhibitor IV

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₁₈H₁₆F₂N₄O₂S

[ Molecular Weight ]:
390.407

[ Exact Mass ]:
390.096191

[ PSA ]:
112.40000

[ LogP ]:
0.80

[ Index of Refraction ]:
1.706

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xi

LY2886721

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream