Eicosapentaenoic acid (ethyl ester)

Names

[ Name ]:
Eicosapentaenoic acid (ethyl ester)

[Synonym ]:
Epadel
5,8,11,14,17-Eicosapentaenoic acid, ethyl ester, (all-Z)-
all-cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester
Eicosapentaenoic acid-D5 ethyl ester
Ethyl icosapentate
ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
E-EPA
AMR 101
ethyl icosapentaenoate
ethyl (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate
(Z,Z,Z,Z,Z)-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
5,8,11,14,17-Eicosapentaenoic acid, ethyl ester, (5Z,8Z,11Z,14Z,17Z)-
Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
Ethyl all cis-5,8,11,14,17-Icosapentaenoate
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate
ethyl all-cis-5,8,11,14,17-icosapentaenoate
ethyl eicosapentaenoate
Ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
EICOSAPENTAENOIC ACID ETHYL ESTER
Timnodonic acid ethyl ester
(5Z,8Z,11Z,14Z,17Z)-Eicosapetaenoic acid ethyl ester
ALL CIS-5,8,11,14,17-EICOSAPENTANOIC ACID ETHYL ESTER
Ethyl (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-icosapentaenoate
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
Ethyl (all cis)-5,8,11,14,17-icosapentaenoate
(all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl ester
Eicosapentaenoic Acid ethyl este
AMR-101
Eicosapentaenoic acid, ethyl ester
Vascepa
OMEGA-3-ACID ESTERS (EPA shown)
Ethyl eicosapentaenoic acid
Icosapent ethyl
MFCD00673476
Eicosapentaenoic acid (ethyl ester)

Biological Activity

[Description]:

Eicosapentaenoic acid ethyl ester (AMR-101) is an omega-3 fatty acid agent.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Jacobson TA. A new pure ω-3 eicosapentaenoic acid ethyl ester (AMR101) for the management of hypertriglyceridemia: the MARINE trial. Expert Rev Cardiovasc Ther. 2012 Jun;10(6):687-695.

[2]. Bays HE, et al. Eicosapentaenoic acid ethyl ester (AMR101) therapy in patients with very high triglyceride levels (from theMulti-center, plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label Extension[MARINE] trial). Am J Cardiol. 2011 Sep 1;108(5):682-690.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
417.0±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₃₄O₂

[ Molecular Weight ]:
330.504

[ Flash Point ]:
103.1±24.0 °C

[ Exact Mass ]:
330.255890

[ PSA ]:
26.30000

[ LogP ]:
7.32

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.496

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2916190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%