CCMI
Names
Biological Activity
[Description]:
CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1].
[Related Catalog]:
[Target]
α7 nAChR[1]
[In Vitro]
CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs[1].
[References]
Chemical & Physical Properties
[ Density]:
1.412±0.06 g/cm3(Predicted)
[ Boiling Point ]:
605.4±55.0 °C
[ Molecular Formula ]:
C19H15Cl2N3O2
[ Molecular Weight ]:
388.24700
[ Exact Mass ]:
387.05400
[ PSA ]:
67.16000
[ LogP ]:
5.52750
Safety Information
[ Hazard Codes ]:
Xn