Lasofoxifene tartrate

Names

[ CAS No. ]:
190791-29-8

[ Name ]:
Lasofoxifene tartrate

[Synonym ]:
lasofoxifene D-tartrate
1-(2-{4-[(1S,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydro-1-naphthalenyl]phenoxy}ethyl)pyrrolidinium chloride
Unii-85X09V2gso
Pyrrolidinium, 1-[2-[4-[(1S,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenoxy]ethyl]-, chloride (1:1)
Lasofoxifene tartrate
Lasofoxifene (Tartrate)

Biological Activity

[Description]:

Lasofoxifene Tartrate is a non-steroidal selective estrogen receptor modulator (SERM).

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR

Research Areas >> Endocrinology

[References]

[1]. Andersson A, et al. Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis. Rheumatology (Oxford). 2015 Sep 30. pii: kev355.

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
572.4ºC at 760 mmHg

[ Melting Point ]:
185 °C(dec.)

[ Molecular Formula ]:
C₃₂H₃₇NO₈

[ Molecular Weight ]:
563.64

[ Flash Point ]:
300ºC

[ PSA ]:
32.70000

[ LogP ]:
6.46860

[ Vapour Pressure ]:
1.05E-13mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0