Spermidine trihydrochloride

Names

[ CAS No. ]:
334-50-9

[ Name ]:
Spermidine trihydrochloride

[Synonym ]:
SPD trihydrochloride
N1-(3-Aminopropyl)butane-1,4-diamine trihydrochloride
N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
1,4-Butanediamine, N-(3-aminopropyl)-, hydrochloride (1:3)
Spermidine hydrochloride
4-Azoniaoctamethylenediammonium trichloride
Spermidine,Trihydrochloride
MFCD00012918
n-(3-aminopropyl)butane-1,4-diamine trihydrochloride
N-(3-aminopropyl)-1,4-butanediamine, trihydrochloride
N-(3-aminopropyl)butane-1,4-diaminetrihydrochloride
Spermidine trihydrochloride
EINECS 206-379-0

Biological Activity

[Description]:

Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

Spermidine plays a crucial role of against abiotic stresses, such as salt, drought, heat, and salinity-alkalinity stresses in tomato, cucumber, rice[1].

[References]

[1]. Zhang L, et al. The Alleviation of Heat Damage to Photosystem II and Enzymatic Antioxidants by Exogenous Spermidine in Tall Fescue. Front Plant Sci. 2017 Oct 12;8:1747.

Chemical & Physical Properties

[ Density]:
0.906 g/cm3

[ Boiling Point ]:
246.6ºC at 760 mmHg

[ Melting Point ]:
257-259 °C(lit.)

[ Molecular Formula ]:
C₇H₂₂Cl₃N₃

[ Molecular Weight ]:
254.629

[ Flash Point ]:
118.1ºC

[ Exact Mass ]:
253.087936

[ PSA ]:
64.07000

[ LogP ]:
3.86120

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ7023000

CHEMICAL NAME :: 1,4-Butanediamine, N-(3-aminopropyl)-, trihydrochloride

CAS REGISTRY NUMBER :: 334-50-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H19-N3.3Cl-H

MOLECULAR WEIGHT :: 254.67

WISWESSER LINE NOTATION :: Z4M3Z &GH 3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 870 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 41,1575,1982

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EJ7023000

[ HS Code ]:
2921290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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