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PTIQ

Names

[ CAS No. ]:
1032822-42-6

[ Name ]:
PTIQ

[Synonym ]:
N-ethylcarbonyl-7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline
EHMTIQ
DMP 543
PTIQ

Biological Activity

[Description]:

PTIQ can suppress MMP-3 production, can enter the brain and provide neuroprotection. PTIQ has anti-inflammatory effects on microglial cells[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Son HJ, et al. A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP. Br J Pharmacol. 2012;165(7):2213-2227.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H17NO3

[ Molecular Weight ]:
235.27900

[ Exact Mass ]:
235.12100

[ PSA ]:
49.77000

[ LogP ]:
1.63340