mGluR2 modulator 2

Names

[ CAS No. ]:
1004614-86-1

[ Name ]:
mGluR2 modulator 2

Biological Activity

[Description]:

mGluR2 modulator 2 (compound 2) is a potent, selective and orally bioavailable mGluR2 positive allosteric modulator with an EC50 value of 0.13 μM. mGluR2 modulator 2 can be used for researching antipsychotic[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR
Research Areas >> Neurological Disease

[Target]

mGluR2:0.13 μM (EC50)


[References]

[1]. Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020;186:111881.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H22FN3

[ Molecular Weight ]:
323.41

Related Compounds