Nrf2 activator-5

Names

[ CAS No. ]:
1012860-13-7

[ Name ]:
Nrf2 activator-5

Biological Activity

[Description]:

Nrf2 activator-5 (compound 1) is a potent Nrf2 activator that can attenuate H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglial cells. Nrf2 activator-5 exhibits antioxidant and anti-inflammatory activities[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2
Research Areas >> Inflammation/Immunology

[References]

[1]. Choi JW, et, al. Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities. Bioorg Chem. 2020 Dec;105:104434.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H30Cl2O6

[ Molecular Weight ]:
497.41

Related Compounds