Pantothenate kinase-IN-1

Names

[ CAS No. ]:
1024168-48-6

[ Name ]:
Pantothenate kinase-IN-1

Biological Activity

[Description]:

Pantothenate kinase-IN-1 (Compound 1) is a pantothenate kinase (PANK) modulator with an IC50 of 0.51 µM against PANK3. Pantothenate kinase-IN-1 has a reasonable ligand efficiency (LipE = 2.8)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

IC50: 0.51 µM (PANK3)[1]


[References]

[1]. Sharma LK, et al. LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg Med Chem. 2021 Dec 15;52:116504.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25N5O

[ Molecular Weight ]:
363.46

Related Compounds