4-Methylanisole-d7

Names

[ CAS No. ]:
1036431-36-3

[ Name ]:
4-Methylanisole-d7

Biological Activity

[Description]:

4-Methylanisole-d7 is the deuterium labeled 4-Methylanisole[1]. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Esther F A Brandon, et al. Implementation of Toxicokinetics in Toxicity studies--Toxicokinetics of 4-methylanisole and Its Metabolites in Juvenile and Adult Rats. Regul Toxicol Pharmacol. 2015 Oct;73(1):55-64.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H3D7O

[ Molecular Weight ]:
129.20800

[ Exact Mass ]:
129.11700

[ PSA ]:
9.23000

[ LogP ]:
2.00360

[ Storage condition ]:
2-8°C

Related Compounds